At Maritime Hair Center, the treatment of androgenetic alopecia is based on personalized combination therapies that effectively inhibit the progression of hair follicle miniaturization and stimulate new hair growth. We implement this technical process through:
The primary cause of male pattern androgenetic alopecia is the hypersensitivity of hair follicles to DHT (dihydrotestosterone), increased levels of this hormone, and elevated levels of free testosterone (unbound to SHBG protein).
It is worth noting that these factors do not have to occur simultaneously – very often, blood hormone levels appear completely normal, yet advanced miniaturization of follicles still occurs due to their genetic hypersensitivity.
Mechanism of action: Testosterone circulating in the body is converted into its active form – DHT – by the 5-alpha reductase enzyme. This hormone binds to receptors within the hair follicles, leading to their gradual weakening, shrinkage, and ultimate loss, which the patient perceives as hair thinning. The highest concentration of DHT-sensitive follicles is located in the temples, hairline, tonsure, and crown areas. The occipital and temporal regions of the scalp are typically free from this sensitivity.
The baseline for halting hair loss is blocking the 5-alpha reductase enzyme, which reduces the amount of destructive DHT circulating in the blood and protects hair follicles from damage.
Lowers blood DHT levels by approximately 60%. It breaks down in the body with a half-life of about 5 hours, while the hormone-lowering effect is maintained for up to 24 hours. Because of this, the medication must be taken consistently every day at the same time.
Acts more potently than finasteride, reducing blood DHT levels by up to approximately 90%. Its terminal elimination half-life in the body is about 5 weeks, and the therapeutic effect can persist for up to 6 months. It is most commonly administered in oral form (daily).
As with any pharmacological treatment, blocking 5-alpha reductase carries a risk of adverse effects. The most frequently reported include:
Another crucial pillar of treatment is Minoxidil, which we apply as a topical lotion, orally, or by combining both forms to achieve maximum results. This drug:
While the risk can never be fully eliminated, modern trichology allows us to reduce systemic side effects to a minimum or eliminate them entirely. The best approach is to bypass the digestive tract and apply the medication locally. At Maritime Hair Center, we provide patients with highly safe alternatives:
Applied locally to the scalp once a day. It targets the problem area precisely, minimizing the medication's concentration in the bloodstream.
Intradermal injection of the medication. It is initially performed in a series of sessions every 2–4 weeks, followed by maintenance treatments. The therapy plan is always tailored individually.
Utilizing natural growth factors contained in the plasma, it intensively stimulates and awakens dormant hair follicles to produce new hair.
Micro-injections of targeted vitamin and nutrient cocktails, providing direct, deep nourishment to the scalp and follicle structures.
Carbon dioxide therapy that revolutionizes microcirculation, heavily oxygenating the tissues and naturally accelerating regenerative processes.
Increases blood flow and nutrient delivery to the hair follicles, boosting growth factor production and activating hair cells.
